HYPOXIA SURVIVAL VARIATIONS IN MALE AND FEMALE MICE AS FUNCTIONS OF CHRONOLOGICAL AND ENVIRONMENTAL-FACTORS

  • 1 January 1978
    • journal article
    • research article
    • Vol. 49  (9) , 1087-1092
Abstract
The inhalation by mice for 20 min of 5.5% O2 in N, performed 29 times over 40 mo. caused a mortality of 49.81%. Correlation coefficients were calculated between hypoxic mortality and different parameters: environmental.sbd.lighting, temperature, hygrometry, barometric pressure; biological.sbd.sex, age, body weight; and chronological.sbd.circadian, circannual, pluriannual. Partial correlation coefficients eliminated several interrelationships and finally point out the statistical significance of transfer from dark to light (P < 0.001), of circadian (P < 0.05) and of circannual (P < 0.01) hypoxic mortality variations. Moreover, a significant (P < 0.001) sex-related difference of mortality (males: 56.94%; females: 41.14%) was observed, independently of the environmental and chronological parameters studied.

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