Disposition, Bioavailability, and Serum Protein Binding of Pentachlorophenol in the B6C3F1 Mouse
- 1 January 1992
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 09 (8) , 1053-1057
- https://doi.org/10.1023/a:1015810629245
Abstract
The toxicokinetics of pentachlorophenol (PCP) were studied in B6C3F1 mice, a strain in which PCP was previously found to be carcinogenic. In a crossover design, doses of 15 mg/kg were given...Keywords
This publication has 16 references indexed in Scilit:
- Separation procedures used to reveal and follow drug—protein bindingJournal of Chromatography B: Biomedical Sciences and Applications, 1990
- Residues of chlorinated phenols and phenoxy acid herbicides in the urine of Arkansas childrenArchives of Environmental Contamination and Toxicology, 1989
- Pentachlorophenol: Environmental partitioning and human exposureArchives of Environmental Contamination and Toxicology, 1989
- Comparative Evaluation of Microultrafiltration Devices for Determination of Protein BindingTherapeutic Drug Monitoring, 1988
- Dose-response relationships for carcinogens: a review.Environmental Health Perspectives, 1987
- DNA-damaging properties and cytotoxicity in human fibroblasts of tetrachlorohydroquinone, a pentachlorophenol metaboliteMutation Research/DNA Repair Reports, 1985
- A general scheme for the incorporation of pharmacokinetics in low-dose risk estimation for chemical carcinogenesis: Example—Vinyl chlorideToxicology and Applied Pharmacology, 1980
- Interspecies variation in liver weight, hepatic blood flow, and antipyrine intrinsic clearance: Extrapolation of data to benzodiazepines and phenytoinJournal of Pharmacokinetics and Biopharmaceutics, 1980
- The effect of purified and commercial grade pentachlorophenol on rat embryonal and fetal developmentToxicology and Applied Pharmacology, 1974
- Metabolism of 14C‐Pentachlorophenol in the MouseActa Pharmacologica et Toxicologica, 1971