Abstract
Keratopacanthoma (KA) is a relatively common tumor believed to be a benign epidermal neoplasm. Patients (90) with 1 or more KA were observed in regard to clinical, therapeutic and prognostic implications. The relationship of KA to internal malignant neoplasms in 78 patients was analyzed. Keratoacanthoma is a disease of the elderly (mean patient age, 64.1 yr). It is associated with other nonmelanoma cutaneous neoplasias in 21% of cases, a figure lower than that seen with squamous cell carcinomas. When solitary, KA is not associated with concurrent or subsequent internal malignant neoplasms more often than would be predicted by population statistics. Therapy is generally curative, but .apprx. 8% of the patients had recurrences. These patients may be successfully treated with several existing modalities.