Optically Active Arthropod Repellents for Use Against Disease Vectors
- 1 January 2000
- journal article
- Published by Oxford University Press (OUP) in Journal of Medical Entomology
- Vol. 37 (1) , 182-186
- https://doi.org/10.1603/0022-2585-37.1.182
Abstract
Optically inactive 1-[3-cyclohexen-1-ylcarbonyl] piperidine and 1-[3-cyclohexen-1-ylcarbonyl]-2-methylpiperidine are repellents against blood-feeding arthropods. Pure stereoisomers of these compounds were synthesized and characterized for use in bioassays. Initial laboratory tests with the malaria vector Anopheles stephensi Liston showed that this species was repelled differentially by the stereoisomers of 1-[3-cyclohexen-1-ylcarbonyl]-2-methylpiperidine. Two stereoisomers were twice as repellent as the other stereoisomers. These results indicate that stereoisomerism influences repellent efficacy in this class of compounds.Keywords
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