Synergistic Effect of Herpes Simplex Virus and Cytosine Arabinoside on Human Chromosomes
- 1 May 1971
- journal article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 7 (5) , 692-695
- https://doi.org/10.1128/jvi.7.5.692-695.1971
Abstract
The combined treatment of cultures of human embryonic lung cells with herpes simplex virus type 2 and cytosine arabinoside produced a significantly increased number of cells containing multiple chromatid and chromosome breaks. The incidence of such cells was found to be approximately two and one half times greater than the additive effects of virus and cytosine arabinoside induced separately and is therefore synergistic.Keywords
This publication has 21 references indexed in Scilit:
- CHROMOSOMAL EFFECTS OF ARABINOSYLCYTOSINE IN A HUMAN DIPLOID CELL STRAINHereditas, 2009
- Chromosomal Aberrations Induced in Barley by LSDScience, 1970
- Chromosome Changes in Human Cells induced by Herpes Simplex, Types 1 and 2Nature, 1969
- Meiotic Chromosome Damage induced by LSD-25Nature, 1968
- Congenital Malformations Induced by Mescaline, Lysergic Acid Diethylamide, and Bromolysergic Acid in the HamsterScience, 1967
- Chromosomal Damage in Human Leukocytes Induced by Lysergic Acid DiethylamideScience, 1967
- Prominent Secondary Constrictions in a Pseudodiploid Human Cell LineCytogenetic and Genome Research, 1966
- Synergistic Effect of 5-Bromodeoxyuridine and Gamma Rays on ChromosomesScience, 1963
- Gross and chromosomal cytology of virus infected Chinese hamster cellsExperimental Cell Research, 1963
- Chromosomal Aberrations Induced by an Animal VirusNature, 1961