Nystatin
- 1 January 1961
- journal article
- research article
- Published by S. Karger AG in Chemotherapy
- Vol. 3 (2) , 108-119
- https://doi.org/10.1159/000219536
Abstract
Nystatin, a polyene antibiotic has broad fungistatic and fungicidal activities; in vivo resistance is unknown; a low-grade in vitro resistance has been reported; oral or topical toxicity is lacking. Nystatin has found its chief application in the treatment of various forms of moniliasis. Infections of the respiratory tract, the sinuses and superficial eye infections due to Aspergillus fumigatus, and isolated muco-cutaneous lesions of histoplasmosis also respond to the antibiotic. Negligible absorption from the gastrointestinal tract and the unsuitability of parenteral routes of administration preclude the use of nystatin in systemic mycoses.Keywords
This publication has 9 references indexed in Scilit:
- NYSTATINAnnals of the New York Academy of Sciences, 2006
- SOME ASPECTS OF THE MODE OF ACTION OF POLYENE ANTIFUNGAL ANTIBIOTICSAnnals of the New York Academy of Sciences, 1960
- MECHANISMS OF ACTION OF ANTIBIOTICS*Annals of the New York Academy of Sciences, 1960
- Significance of Nystatin Uptake for Its Antifungal ActionExperimental Biology and Medicine, 1959
- ABSORPTION OF NYSTATIN BY MICROORGANISMSJournal of Bacteriology, 1959
- Interactions Between Phosphate and Nystatin in Candida stellatoideaExperimental Biology and Medicine, 1958
- Cultivation of Human Epithelial Cells in Tissue Culture.Experimental Biology and Medicine, 1956
- The Roller Tube Tissue Culture Technic in the Evaluation of the Primary Irritancy Producing Capacity of Topical Medicaments and Chemicals1Journal of Investigative Dermatology, 1956
- Fungicidin, an Antibiotic Produced by a Soil ActinomyceteExperimental Biology and Medicine, 1951