PIROXICAM (CP 16171) IN RHEUMATOID-ARTHRITIS - A CONTROLLED CLINICAL-TRIAL WITH NOVEL ASSESSMENT TECHNIQUES

  • 1 January 1977
    • journal article
    • research article
    • Vol. 4  (4) , 393-404
Abstract
Piroxicam (CP 16171), a new nonsteroidal anti-inflammatory agent, decreased pain, stiffness and inflammation and increased the patient''s ability to perform tasks in a double-blind study of patients with active definite rheumatoid arthritis, poorly controlled despite standard therapy. Clinically and statistically significant improvement occurred in grip strength, walking time and morning stiffness, and in patient and physician evaluation. Of the piroxicam-treated patients, 75% increased their daily activities. Three patients treated with the tablet form of piroxicam developed gastrointestinal ulcerations. Another patient developed Fe deficiency anemia.

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