ACID-BASE STATUS OF BIOLOGICAL-FLUIDS - AMOUNT OF ACID, KIND OF ACID, ANION-CATION DIFFERENCE, AND BUFFER VALUE

  • 1 January 1983
    • journal article
    • research article
    • Vol. 43  (2) , 103-109
Abstract
A formal concept of amount of substance of acid and base is proposed which is based on the change in extent of protolytic equilibria in an arbitrary reference state for the components of the system concerned and equally consistent with the Bronsted-Lowry terminology, the older medical anion-cation terminology and the operational principle of titration. This concept allows formulations of the acid-base status of biological fluids in accordance with various types of physiological, biochemical or clinical problems. Finally, a general expression for buffer value is presented which is vaild for any acid, base or ampholyte at any pH.

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