Effects of cerulenin, an inhibitor of fatty acid synthesis on reconstitution of the dental basement membrane
- 1 January 1990
- journal article
- research article
- Published by Wiley in Biology of the Cell
- Vol. 69 (1) , 27-33
- https://doi.org/10.1016/0248-4900(90)90325-w
Abstract
When trypsin-dissociated enamel organs and dental papillae were recombined in the presence of cerulenin - an antibiotic which is a potent inhibitor of fatty acid synthesis - the newy synthesized basement membrane seemed defective in a dose-dependent manner. The three-dimensional relationship between the basement membrane components and the plasma membrane appears to be regulated in part by lipids.Keywords
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