Mating between two balanced translocation carriers in two unrelated families
- 1 December 1983
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 65 (2) , 165-168
- https://doi.org/10.1007/bf00286655
Abstract
Partial trisomy 9p and a 13/14 translocation occurred in the daughter of a t(5;9)(p15;p12) mother and a t(13;14) (p11;q11) father. Two additional offspring displayed a normal karyotype and a translocation trisomy 13 respectively. Two first cousins, selected for chromosome analysis because of a spontaneous abortion, were found to have an identical translocation t(14;21)(p11;q11). Their second pregnancy was monitored by midtrimester amniocentesis and disclosed a balanced fetus. The different zygotic chromosome constitutions and the counselling problems in the marriages between two balanced translocation carriers are discussed.This publication has 4 references indexed in Scilit:
- Genetic risks for familial reciprocal translocations with special emphasis on those leading to 9p, 10p and 12p trisomiesAnnals of Human Genetics, 1982
- The offspring of marriage between two first cousins with the same reciprocal translocation t(2;7)(p11;q31)Human Genetics, 1980
- [2 familial translocations occurring together in each of 2 sisters, one balanced, the other partial trisomic 10q].1972
- [Study of progeny of individuals bearing a t(DqDq) translocation].1970