Biotinylation of Histones Represses Transposable Elements in Human and Mouse Cells and Cell Lines and in Drosophila melanogaster3
Open Access
- 1 December 2008
- journal article
- Published by Elsevier in Journal of Nutrition
- Vol. 138 (12) , 2316-2322
- https://doi.org/10.3945/jn.108.098673
Abstract
Transposable elements such as long terminal repeats (LTR) constitute ∼45% of the human genome; transposition events impair genome stability. Fifty-foKeywords
This publication has 39 references indexed in Scilit:
- Epigenetic regulation of chromatin structure and gene function by biotin: are biotin requirements being met?Nutrition Reviews, 2008
- Holocarboxylase synthetase regulates expression of biotin transporters by chromatin remodeling events at the SMVT locusThe Journal of Nutritional Biochemistry, 2008
- K12-biotinylated histone H4 marks heterochromatin in human lymphoblastoma cellsThe Journal of Nutritional Biochemistry, 2007
- Transposable elements and the epigenetic regulation of the genomeNature Reviews Genetics, 2007
- Epigenetic memory at malaria virulence genesProceedings of the National Academy of Sciences, 2007
- 5-Aza-2′-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivationOncogene, 2006
- GREM, a technique for genome-wide isolation and quantitative analysis of promoter active repeatsNucleic Acids Research, 2006
- Role of Acetylases and Deacetylase Inhibitors in IRF‐1‐Mediated HIV‐1 Long Terminal Repeat TranscriptionAnnals of the New York Academy of Sciences, 2004
- Progesterone receptor gene inactivation and CpG island hypermethylation in human leukemia cancer cellsFEBS Letters, 2004
- Translating the Histone CodeScience, 2001