Comparison of Fructosamine With Glycosylated Hemoglobin and Plasma Proteins as Measures of Glycemic Control
- 1 May 1988
- journal article
- research article
- Published by American Diabetes Association in Diabetes Care
- Vol. 11 (5) , 433-436
- https://doi.org/10.2337/diacare.11.5.433
Abstract
The relative value of fructosamine as an alternative to glycosylated hemoglobin (HbA1) and other measures of glycemic control was assessed in 100 insulin-dependent (IDDM) and 104 non-insulin-dependent (NIDDM) diabetic patients. We measured HbA1 (by electrophoretic and affinity methods), plasma glucose, glycosylated plasma proteins, and fructosamine in blood taken at a single clinic visit. The values were compared both by correlation analysis and by considering whether the various indices of glycemic control placed the patients in the same clinical decision categories as they were in by the HbA1 (affinity) result. Fructosamine correlated moderately well with HbA1 (affinity; r = .8) and placed 71% of IDDM and 72% of NIDDM patients in the same clinical category of good, moderate, or poor control. Differences can probably be partly attributed to the different periods over which HbA1 and fructosamine reflect average glycemia and partly to imprecision.Keywords
This publication has 1 reference indexed in Scilit:
- Glycosylated Serum Protein and Hemoglobin A_1 Levels to Measure Control of GlycemiaAnnals of Internal Medicine, 1981