PROPAGATION, AND EXTENSION OF EXCITATORY EFFECTS, OF THE NERVE ACTION POTENTIAL ACROSS NONRESPONDING INTERNODES

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Abstract
When adjacent nodes of a nerve fiber (Rana pipiens) are anodally depressed, the proximal one to block, the distal one beyond block, a nerve impulse, itself blocked, may so condition both that a 2d impulse will be conducted through. By anodally raising the threshold at one node, and cathodally lowering the threshold at the next node, the local action potential can be made to lose a quantum of negativity while remaining diphasic; this is taken to mean that the action potential is reinitiating the impulse across at least one nonresponding internodal segment. These remote effects of a blocked impulse are referred to the action potential, which, on the basis of data derived through polarization block, is estimated to have 2.5 times the strength required for propagation. Nervous propagation and transmission evidently can be electrical.