Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model
Top Cited Papers
- 1 February 2007
- Vol. 53 (3) , 337-351
- https://doi.org/10.1016/j.neuron.2007.01.010
Abstract
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This publication has 61 references indexed in Scilit:
- Age-Dependent Neurofibrillary Tangle Formation, Neuron Loss, and Memory Impairment in a Mouse Model of Human Tauopathy (P301L)Journal of Neuroscience, 2005
- Tau Suppression in a Neurodegenerative Mouse Model Improves Memory FunctionScience, 2005
- Accumulation of Filamentous Tau in the Cerebral Cortex of Human Tau R406W Transgenic MiceThe American Journal of Pathology, 2005
- Retarded Axonal Transport of R406W Mutant Tau in Transgenic Mice with a Neurodegenerative TauopathyJournal of Neuroscience, 2004
- Alzheimer's Disease Is a Synaptic FailureScience, 2002
- High Prevalence of Mutations in the Microtubule-Associated Protein Tau in a Population Study of Frontotemporal Dementia in the NetherlandsAmerican Journal of Human Genetics, 1999
- Transneuronal Degeneration in the Spread of Alzheimer's Disease Pathology: Immunohistochemical Evidence for the Transmission of Tau HyperphosphorylationNeurobiology of Disease, 1997
- A vector for expressing foreign genes in the brains and hearts of transgenic miceGenetic Analysis: Biomolecular Engineering, 1996
- Abnormal tau phosphorylation at Ser396 in alzheimer's disease recapitulates development and contributes to reduced microtubule bindingNeuron, 1993
- Glial fibrillary acidic protein and βA4 protein deposits in temporal lobe of aging brain and senile dementia of the Alzheimer type: Relation with the cognitive state and with quantitative studies of senile plaques and neurofibrillary tanglesJournal of Neuroscience Research, 1990