Chemical Studies on the Antibiotic Esperin
- 1 November 1959
- journal article
- research article
- Published by Oxford University Press (OUP) in Bulletin of the Agricultural Chemical Society of Japan
- Vol. 23 (6) , 536-547
- https://doi.org/10.1080/03758397.1959.10857610
Abstract
Esperin is an acidic antibiotic with a molecular formula of C39H67N5O11 and, on hydrolysis with acid, it afforded l-aspartic acid, l-glutamic acid, l-valine, l-leucine, d-leucine and 2-tridecenoic acid. By treatment with alkali, esperin was transformed to esperinic acid, C39H69N5O12, which was shown to be β-hydroxytridecanoyl-glutamyl-aspartyl-valyl-leucyl-leucine. From chemical and physical studies, esperin was proved to be the lactone of esperinic acid, represented by the formula III.This publication has 11 references indexed in Scilit:
- The kinetics of acid hydrolysis of dipeptidesBiochemical Journal, 1956
- ON THE STRUCTURE OF LYSOZYMEThe Journal of Biochemistry, 1955
- The amino acid sequence in bacitracin ABiochemical Journal, 1954
- Influence of Optically Active Acyl Groups on the Enzymatic Hydrolysis of N-Acylated-L-amino AcidsJournal of the American Chemical Society, 1954
- ON THE STRUCTURE OF LYSOZYMEThe Journal of Biochemistry, 1954
- Quantitative Determination of Amino AcidsAnalytical Chemistry, 1954
- A PARTIAL SEQUENCE OF AMINO ACIDS IN PERFORMIC ACID-OXIDIZED VASOPRESSINJournal of Biological Chemistry, 1954
- PAPER CHROMATOGRAPHY OF SOME LOWER PEPTIDESJournal of Biological Chemistry, 1951
- PAPAIN RESOLUTION OF dl-TRYPTOPHAN; OPTICAL SPECIFICITY OF CARBOXYPEPTIDASEJournal of Biological Chemistry, 1949
- THE SPECIFICITY OF CARBOXYPEPTIDASEJournal of Biological Chemistry, 1946