Thyroxine Secretion Rates During Food Restriction in Rats.

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Abstract
Mature female Sprague-Dawley-Rolfsmeyer rats with a mean food consumption of 5.26 g/100 g BW of Purina Lab Chow were subjected to 8, 17, 22 and 48% food restriction. Thyroxine secretion rates (TSR) were determined beginning three and seventeen days later. Only 48% restriction resulted in a significant reduction in TSR during initial period (28%). In second period a 22% restriction resulted in a significant 42% and 48% restriction resulted in a highly significant 54% decrease in TSR.