INFLUENCE OF HYDROCORTISONE ON UPTAKE AND ELIMINATION OF 32P-LABELLED E. COLI BY RAT POLYMORPHONUCLEAR NEUTROPHILS (PMN) IN VITRO
- 15 August 2009
- journal article
- research article
- Published by Wiley in Acta Pathologica Microbiologica Scandinavica Section C Immunology
- Vol. 84C (2) , 131-134
- https://doi.org/10.1111/j.1699-0463.1976.tb00010.x
Abstract
Hydrocortisone was tested for inhibition of uptake and of elimination of Escherichia coli by monolayers of rat peritoneal PMN. 32P was used to label the bacteria and their degradation products eliminated from the phagocytes. The cellular uptake was reduced by hydrocortisone (1-2 mg/ml) in the presence and absence of serum, while the elimination of bacterial label was reduced by .gtoreq. 0.5 mg/ml concentrations of the drug.Keywords
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