Total Serum Protein Concentration and Total Weight of Circulating Protein in the Rat

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Abstract
The total circulating serum protein and total protein serum concn. in the rat were shown to be related to body surface area (by the formula of Carman and Mitchell) over a wide range, including the range of puberty. The sex difference in total serum protein concn. is of sufficient magnitude to require its consideration in planning and interpreting expts. In the general formula f(x) equals A plus Bx, where body surface in sq. cm. is represented by x,. the following constants were given: for f(x) representing blood vol. in ml. for combined sexes, plasma vol. in ml. for combined sexes, total circulating protein in mg. for combined sexes, serum protein concn. in g.% for male, and serum protein concn. in g.% for male, values of A are -1.91, -0.710, -142, 3.15, and 2. 85 respectively, and values of B are 0.0390[plus or minus] 0.0016, 0.0211[plus or minus]0.0008, 1.49[plus or minus]0.04, 0.00617[plus or minus]0.0024, and 0.00920[plus or minus]0.0026.
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