Gammaflow: A Completely Automated Radioimmunoassay System
- 15 October 1976
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 194 (4262) , 270-276
- https://doi.org/10.1126/science.184530
Abstract
The details and initial results of a completely automated on-line radioimmunoassay system, Gamma-flow are reported. This system combines the sample or standard with the labeled ligand and antibody, incubates the samples, separates and determines the amount of labeled ligand bound, and then computes the amount of the unknown sample by comparison to standard curves. The complete operation, at the rate of 20-40 samples/h, can take place in the absence of any human intervention. Automated radioimmunoassays for digoxin, cyclic AMP, cyclic GMP, insulin, angiotensin I and thyroxine are described.This publication has 13 references indexed in Scilit:
- Kinetics of interactions between antibodies and haptensBiochemistry, 1975
- Immunoassay of Thyroxine in Unextracted Human SerumJournal of Clinical Endocrinology & Metabolism, 1973
- RADIOIMMUNOASSAY FOR TRIIODOTHYRONINE IN HUMAN SERUMActa Endocrinologica, 1973
- Serum Cardiac Glycoside Assay Based upon Displacement of 3 H-Ouabain from Na-K ATPaseCirculation, 1972
- A RAPID SEMI‐AUTOMATED METHOD FOR THE MEASUREMENT OF HUMAN CHORTONIC SOMATOMAMMOTROPHIN. THE NORMAL RANGE IN THE THIRD TRIMESTER AND ITS RELATION TO FETAL WEIGHTBJOG: An International Journal of Obstetrics and Gynaecology, 1971
- Determination of Therapeutic and Toxic Serum Digoxin Concentrations by RadioimmunoassayNew England Journal of Medicine, 1969
- RADIOIMMUNOASSAY FOR THE MEASUREMENT OF ADENOSINE 3′,5′-CYCLIC PHOSPHATEProceedings of the National Academy of Sciences, 1969
- Immunoassay of Insulin: Two Antibody System: Plasma Insulin Levels of Normal, Subdiabetic and Diabetic RatsDiabetes, 1963
- IMMUNOASSAY OF ENDOGENOUS PLASMA INSULIN IN MANJournal of Clinical Investigation, 1960
- QUANTITATIVE ASPECTS OF THE REACTION BETWEEN INSULIN AND INSULIN-BINDING ANTIBODYJournal of Clinical Investigation, 1959