Modulation by Thyroxine of the Amount of Lactase Protein in the Jejunum of Adult Rats
- 1 July 1986
- journal article
- research article
- Published by S. Karger AG in Enzyme
- Vol. 36 (3) , 216-220
- https://doi.org/10.1159/000469295
Abstract
Adult rats starved for 48 h received a daily injection of thyroxine over a 3-day period before they were killed. When compared to nourished animals, starvation provoked a 4- to 5-fold increase in immunoreactive lactase protein, which paralleled a similar stimulation of lactase activity in the brush border membranes of the proximal jejunum. Exogenous thyroxine completely inhibited the starvation-induced increase in immunoreactive lactase protein in both the intracellular and the brush border membranes.Keywords
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