INFLUENCE OF INCREASED TEMPERATURE ON THE INHIBITION OF RAT OSTEO-SARCOMA CELL - MULTIPLICATION INVITRO BY INTERFERON

  • 1 January 1980
    • journal article
    • research article
    • Vol. 33  (7) , 239-241
Abstract
Purified rat interferon preparations proved effective in inhibiting cell multiplication in a rat osteosarcoma cell line. A pronounced increase in the inhibitory activity was found with increasing temperature. At 39.degree. C, 20 interferon units/ml appeared to be cytotoxic whereas incubation of cells with 2000 interferon units/ml at 35.degree. C resulted in a cytostatic effect.