The Transport of Endogenous Vitamin B12 in Normal Human Serum
- 1 July 1976
- journal article
- research article
- Published by Portland Press Ltd. in Clinical Science
- Vol. 51 (1) , 47-52
- https://doi.org/10.1042/cs0510047
Abstract
1. Serum from normal subjects has been chromatographed on Sephadex G-200 columns and the fractions containing transcobalamins 0, I and II have been identified. 2. The fractions corresponding to transcobalamin I contained, on average, 90% of the endogenous vitamin B12. Only 3% was attached to transcobalamin 0, and 7% was bound to transcobalamin II.Keywords
This publication has 8 references indexed in Scilit:
- Studies on the Site of Synthesis of Transcobalamin-IIExperimental Biology and Medicine, 1968
- Vitamin B12-binding Proteins in Normal and Leukemic Human Leukocytes and SeraScandinavian Journal of Clinical and Laboratory Investigation, 1968
- Results with radioisotopic assay of serum B12using serum binding agentJournal of Clinical Pathology, 1967
- Delivery of Co57B12 to Erythrocytes from α and β Globulin of Normal, B12-Deficient, and Chronic Myeloid Leukemia SerumBlood, 1967
- Molecular Weights of Vitamin B12Binding Proteins in Human Serum Determined by Sephadex G-200 Gel FiltrationScandinavian Journal of Clinical and Laboratory Investigation, 1967
- The vitamin B12-binding protein in human leukocytesBiochimica et Biophysica Acta (BBA) - General Subjects, 1966
- The Binding of Vitamin B12 Added in Vitro and in Vivo to Normal Human Serum Proteins Separated on Ion Exchange CelluloseScandinavian Journal of Haematology, 1965
- OBSERVATIONS ON THE BOUND FORM OF VITAMIN B12 IN HUMAN SERUMJournal of Biological Chemistry, 1954