Human Red Cell Galactose-1-Phosphate Uridylyltransferase (EC 2.7.7.12)
- 31 December 1979
- journal article
- research article
- Published by S. Karger AG in Human Heredity
- Vol. 30 (1) , 27-32
- https://doi.org/10.1159/000153084
Abstract
The electrophoretically detectable phenotypes of human red cell galactose-1-phosphate uridylyltransferase (GALT) were determined in 2074 unrelated Danes. The gene frequencies were: GALT1 = 0.9233 and GALT2 = 0.0767. The segregation of phenotypes in 765 mother-child pairs was consistent with autosomal codominant inheritance. One apparent mother-child incompatibility with respect to phenotypes was observed which appeared to be due to the segregation of a silent gene. The results of an investigation of 248 paternity cases are reported, and the application of the GALT polymorphism to paternity cases is discussed.Keywords
This publication has 5 references indexed in Scilit:
- Improved technique for electrophoresis of human galactose-1-P uridyl transferase (EC 2.7.7.12)Human Genetics, 1977
- Human Red Cell Acid Phosphatase: Quantitative Evidence of a Silent Gene P°, and a Danish Population StudyHuman Heredity, 1976
- Polymorphism of Human Red Cell Adenosine Deaminase, Esterase D, Glutamate Pyruvate Transaminase and Galactose-1-Phosphate-Uridyltransferase in the Swiss PopulationHuman Heredity, 1975
- Electrophoretic Variation of Galactose-1-Phosphate UridyltransferaseScience, 1966
- Galactosemia, a congenital defect in a nucleotide transferaseBiochimica et Biophysica Acta, 1956