Glucose-6-Phosphate Dehydrogenase and Detoxification of Hydrogen Peroxide in Human Erythrocytes
- 1 December 1961
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 134 (3492) , 1756-1757
- https://doi.org/10.1126/science.134.3492.1756
Abstract
Human erythrocytes with deficient glucose-6-phosphate dehydrogenase levels are unable to maintain their levels of reduced glutathione in the presence of low-level, steady-state concentrations of hydrogen peroxide. This finding has bearing on the biochemical mechanisms of drug-induced hemolytic anemia.Keywords
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