The effect of cyclic AMP on Na+ and K+ transport systems in mouse macrophages
- 1 May 1985
- journal article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 41 (5) , 666-667
- https://doi.org/10.1007/bf02007710
Abstract
Exogenous cyclic AMP (cAMP) inhibits the Na+, K+-cotransport system and stimulates the Na+, K+-pump and Na+, Ca2+ exchange in mouse macrophages. These effects are enhanced by inhibition of phosphodiesterase with methylisobutylxanthine (MIX). MIX alone showed little or no effect. A similar response was observed after stimulation of endogenous production of cAMP by isoproterenol.Keywords
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