LINEAR GROWTH RESPONSES OF BOYS TO PROLONGED TREATMENT WITH CHORIONIC GONADOTROPIN
- 1 April 1951
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 11 (4) , 343-359
- https://doi.org/10.1210/jcem-11-4-343
Abstract
The height and linear growth of sexually underdeveloped boys, measured before, during and after prolonged treatment with chorionic gonadotropin, have been evaluated statistically. Avg. values (Burgess) for boys the same age have been used as "controls." During treatment periods of from 1-4.5 yrs. the growth rate rose from the avg. level to one significantly above it. The group height, significantly below avg. at the start, rose to avg. Subsequently, both values remained within avg. limits. A yr. of treatment started at ages 11 through 15 stimulated more growth than did treatment of younger (7-11 yrs. old) or older (16 yrs. old) patients. Growth benefits of prolonged treatment showed no significant decline until the 3d yr. A schedule for chorionic gonadotropin treatment of similar cases is suggested.Keywords
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