Role of codon 160 in the sensitivity of human O6-alkylguanine-DNA alkyltransferase to O6-benzylguanine

This publication has 18 references indexed in Scilit:

• Phase I trial of O6-benzylguanine for patients undergoing surgery for malignant glioma.
  Journal of Clinical Oncology, 1998
• O6-benzylguanine in humans: metabolic, pharmacokinetic, and pharmacodynamic findings.
  Journal of Clinical Oncology, 1998
• Simultaneous determination of O6-benzylguanine and 8-oxo-O6-benzylguanine in human plasma by reversed-phase high-performance liquid chromatography
  Journal of Chromatography B: Biomedical Sciences and Applications, 1997
• The potential role of glycine-160 of human O6-alkylguanine-DNA alkyltransferase in reaction with O6-benzylguanine as determined by site-directed mutagenesis and molecular modelling comparisons
  Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1997
• Repair of O6-Benzylguanine by the Escherichia coli Ada and Ogt and the Human O6-Alkylguanine-DNA Alkyltransferases
  Journal of Biological Chemistry, 1997
• A polymorphism at codon 160 of human O⁶ methylguanine-DNA methyltransferase gene in young patients with adult type cancers and functional assay
  Carcinogenesis: Integrative Cancer Research, 1995
• Modulation of O6-alkylguanine alkyltransferase-directed DNA repair in metastatic colon cancers.
  Journal of Clinical Oncology, 1995
• Activation of Human O6-Alkylguanine-DNA Alkyltransferase by DNA
  Biochemistry, 1994
• Mechanism of inactivation of human O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine
  Biochemistry, 1993
• Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents.
  Proceedings of the National Academy of Sciences, 1990