Oxidative enzymes in muscular dystrophy

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Abstract
Normal mouse muscular tissue exhibits similar pattern of both succinic and hydroxybutyric dehydrogenase activity, with succinic dehydrogenase being more intense. In dystrophic muscle, there is little change in succinic dehydrogenase activity until atrophy is severe, but hydroxybutyric dehydrogenase becomes much more active. The relationship of these changes to the disease process is not immediately evident.