Hyperthyroidism and diabetes mellitus. An analysis of 70 patients

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Abstract
Nine patients had masked hyperthyroidism with weight loss as the main sign. Diabetic control deteriorated in 28-48 insulin-dependent patients and in 4 of 22 taking hypoglycemic agents orally. Recurrent ketoacidosis occurred in 2. Insulin requirements increased in 11 of 48 by 25%-100% (mean, 50%). Following treatment of the hyperthyroidism, insulin requirements decreased in 13 of 48 by 20-100% (mean, 35%). Four of 22 patients were changed from orally ingested hypoglycemic drugs to insulin. Because of similar symptoms, underlying hyperthyroidism must be considered in any patient whose diabetes is poorly controlled.