Hydroxylation of ansamitocin P-3.
- 1 January 1981
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 34 (12) , 1591-1595
- https://doi.org/10.7164/antibiotics.34.1591
Abstract
Ansamitocin P-3 was converted into 15-hydroxyansamitocin P-3 (PHO-3), C32H43ClN2O10, and 15-epi-15-hydroxyansamitocin P-3 (epi-PHO-3), C32H43ClN2O10, by actinomycetes. PHO-3 was identical to deacetylmaytanbutacine and epi-PHO-3 was a new compound. The configuration at C15 was elucidated as R for PHO-3 and S for epi-PHO-3 on the basis of their physicochemical properties and X-ray analysis of epi-PHO-3.This publication has 6 references indexed in Scilit:
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