Use of the Tritiated Thymidine-Labelling Index of the Myeloblast-Promyelocyte Pool for the Identification of the Leukemic Population in Oligoblastic Leukemia
- 1 January 1981
- journal article
- research article
- Published by S. Karger AG in Acta Haematologica
- Vol. 66 (3) , 181-186
- https://doi.org/10.1159/000207117
Abstract
The bone marrow myeloblast-promyelocyte-labelling index of 32 patients with oligoblastic leukemia was studied at diagnosis and during the course of the disease. A low value ( < 0.17) or a decrease in the labelling index is suggestive of a poor prognosis with development into acute myeloblastic leukemia. Leukemic myeloblasts are characterized by their inability to differentiate and their low labelling index. The low labelling index or the decrease in this labelling index are, thus, an indication of an increase in the leukemic population.This publication has 1 reference indexed in Scilit:
- Proliferative Activity of the Cells of Acute Leukaemia in Relapse and in Steady StateActa Haematologica, 1967