Facilitation of Development of Resistance to Morphine Analgesia by Desglycinamide 9 -Lysine Vasopressin
- 1 May 1974
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 71 (5) , 1852-1856
- https://doi.org/10.1073/pnas.71.5.1852
Abstract
Desglycinamide(9)-lysine vasopressin facilitates development of resistance to the analgesic action of morphine in mice if morphine is administered before the peptide. Desglycinamide(9)-lysine vasopressin is not a morphine antagonist, and does not appear to cause either hyperalgesia or alteration of the response to the technique used for evaluating analgesia.Keywords
This publication has 7 references indexed in Scilit:
- INVESTIGATION OF PHARMACOLOGIC AND BEHAVIORAL TOLERANCE TO MORPHINE IN RATS1973
- Dissociation of the behavioural and endocrine effects of lysine vasopressin by tryptic digestionBritish Journal of Pharmacology, 1972
- Effect of Corticotropin and Desglycinamide 9 -Lysine Vasopressin on Suppression of Memory by PuromycinProceedings of the National Academy of Sciences, 1972
- Pituitary peptides. An octapeptide that stimulates conditioned avoidance acquisition in hypophysectomized rats.1971
- Inhibition of the development of tolerance to morphine in rats by drugs which inhibit ribonucleic acid or protein synthesisBritish Journal of Pharmacology, 1970
- Memory in Mice Analyzed with AntibioticsScience, 1967
- SYNTHETIC ANALGESICS .2. DITHIENYLBUTENYLAMINES AND DITHIENYLBUTYLAMINES1953