Dissociation of the behavioural and endocrine effects of lysine vasopressin by tryptic digestion
Open Access
- 1 May 1972
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 45 (1) , 118-122
- https://doi.org/10.1111/j.1476-5381.1972.tb09582.x
Abstract
1 . Lysine vasopressin induces resistance to extinction of active avoidance behaviour (De Wied, 1971). 2 . Digestion of lysine vasopressin with trypsin almost completely destroys the pressor-, antidiuretic-, oxytocic- and corticotrophin-releasing factor activities of lysine vasopressin, but does not materially influence its effect on the maintenance of an avoidance response.Keywords
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