Biochemistry of Parkinson's disease
- 1 January 1963
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 13 (1) , 56
- https://doi.org/10.1212/wnl.13.1.56
Abstract
The urinary excretion of 5HIAA, a metabolite of serotonin, was studied in 27 patients with Parkinson''s disease and in 56 normal subjects. This excretion was found to be significantly decreased when the disease was present. The serum Mg level in 28 patients with parkin-sonism was found to be significantly decreased compared with that of 20 normal persons. The correlation between these 2 findings is discussed in relation to the etiology of some of the symptoms of Parkinson''s disease.Keywords
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- Studies on 5-hydroxytryptophan decarboxylase. I. In vitro inhibition and substrate interactionArchives of Biochemistry and Biophysics, 1959
- Assay and Importance of Serotonin and its MetabolitesAmerican Journal of Clinical Pathology, 1958