MAXIMUM-LIKELIHOOD MAP OF CHROMOSOME-1

  • 1 January 1979
    • journal article
    • research article
    • Vol. 31  (6) , 680-696
Abstract
Thirteen loci are mapped on chromosome 1 from genetic evidence. The maximum likelihood map presented permits confirmation that Scianna (SC) and a 14th locus, phenylketonuria (PKU), are on chromosome 1, although the location of the latter on the PGM1[phosphoglucomutase-1]-AMY [amylase] segment is uncertain. Eight other controversial genetic assignments are rejected, providing a practical demonstration of the resolution which maximum likelihood theory brings to mapping.