Clinical Epidemiology of Symptomatic Primary Herpetic Infection in Children.

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Abstract
We have studied a series of 50 chidlren with clinical primary herpetic infection during 1975-1985. Our data confirm: absence of sex differences and seasonal variations, a peak age of incidence between 6 and 24 months, a prevalence of patietns of lower social status, evidence of recurrent herpes labialis as the most frequent source of infection, and frequency of herpes simplex virus 1 gingivostomatitis. The relevant findings of this study were as follows: 1) herpes simplex virus 2 was isolated in 10% of the patients, 2) 6% of cases occurred in the first six months of life, 3) infection was multifocal in 36% of cases, 4) autoinoculation was a frequent route of transmission of genital primary infection in young children, 5) herpetic Kaposi-Juliusberg''s pustulosis in infants with atopic dermatitis was the most severe presentation of primary infection and should be more adequately prevented.

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