5-HYDROXYTRYPTAMINE AND HISTAMINE AS MEDIATORS OF THE VASCULAR INJURY PRODUCED BY AGENTS WHICH DAMAGE MAST CELLS IN RATS

Abstract
Each of the four agents, ovomucoid, dextran, 48/80, and testis extract, when injected beneath the skin of the dorsa of the paws of rats produces a local vascular injury characterized by a protein-rich edema. Each agent also produces damage to mast cells.