Factor I (C3b Inactivator) Polymorphism among Five Populations in Eurasia
- 1 January 1988
- journal article
- research article
- Published by S. Karger AG in Human Heredity
- Vol. 38 (2) , 91-94
- https://doi.org/10.1159/000153764
Abstract
Factor I (C3b inactivator) polymorphism in the Japanese (in Western and Southern Japan), Taiwanese, Nepalese and French was studied using isoelectric focusing on polyacrylamide gels. The exposure of passively blotted nitrocellulose membranes to glutaraldehyde vapor facilitated the subsequent immunodetection of a low concentration of factor I and permitted the reliable identification of the three phenotypes determined by two codominant alleles FI*A and FI*B. The data indicated a west-to-east genocline, ranging from France to Western Japan, in which FI*A changed from 0.006 to 0.120.This publication has 9 references indexed in Scilit:
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