AMYLASE IN FALLOPIAN-TUBE AND SEROUS OVARIAN NEOPLASMS - IMMUNOHISTOCHEMICAL LOCALIZATION

  • 1 January 1982
    • journal article
    • research article
    • Vol. 106  (1) , 17-20
Abstract
The cellular localization of amylase in normal [human] Fallopian tubes and serous ovarian neoplasms was studied using an indirect immunoperoxidase technique. The primary antiserum was against human pancreatic amylase, and inhibited ovarian tumor amylase as well. Amylase was present in normal endosalpingeal epithelium and in the epithelial cells of benign, borderline and malignant serous ovarian tumors. A mucinous cystadenoma was studied and contained no amylase. This localization suggests that amylase production by serous ovarian neoplasms reflects the endosalpingeal differentiation of these tumors. Antibody to amylase may be potentially useful in distinguishing serous ovarian tumors from other forms of ovarian neoplasia.