Detection of Agents which Interfere with the Immune Response
- 1 August 1961
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 107 (4) , 796-799
- https://doi.org/10.3181/00379727-107-26758
Abstract
A screening test is described for materials which suppress the immune response during its inductive phase. This test is based on the formation of hemagglutinins to sheep red blood cells in mice. 6-Mercap-topurine, 6-thioguanine and their S-imidazolyl derivatives, B.W. 57-322 and B.W. 57-323, show high activity.Keywords
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