Occupational Medicine

Abstract
Neurologic DisordersThe tendency of certain workplace toxins, including organic solvents such as n-hexane, metals such as lead and arsenic, and certain organophosphate compounds, to cause profound and occasionally irreversible damage to the axons of peripheral nerves has been known for several decades.133 The irreversible central nervous system effects of related compounds have also been well characterized in defined settings: the organic psychosis caused by the solvent carbon disulfide, the diffuse encephalopathy observed in glue sniffers exposed to toluene, and the devastating consequences of lead intoxication in children, for example.134 135 136 In the past several years a new and far . . .