Scanning Electron Microscopy of Human Urine and Purified Tamm-Horsfall's Glycoprotein
- 1 January 1988
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Urology and Nephrology
- Vol. 22 (4) , 313-315
- https://doi.org/10.3109/00365598809180806
Abstract
Dialyzed and dehydrated human urine and purified Tamm-Horsfall's glycoprotein revealed similar morphology by scanning electron microscopy. Single filaments, with diameters between 15–45 nm, splitting off and merging with thicker fibers at irregular intervals made up a three-dimensional meshwork with submicrometer pores. The resulting “fishing net” is capable of trapping microorganisms and may facilitate their elimination from the urinary tract by micturition. Tamm-Horsfall's glycoprotein may accordingly be a factor protecting against urinary tract infections.Keywords
This publication has 13 references indexed in Scilit:
- Ultrastructural localization of Tamm-Horsfall glycoprotein (THP) in rat kidney as revealed by protein A-gold immunocytochemistryHistochemistry and Cell Biology, 1985
- Structure and Function of MucusPublished by Springer Nature ,1982
- AUTOANTIBODIES TO TAMM-HORSFALL PROTEIN, A TOOL FOR DIAGNOSING THE LEVEL OF URINARY-TRACT INFECTIONThe Lancet, 1976
- Morphological and conformational studies of Tamm-Horsfall urinary glycoproteinArchives of Biochemistry and Biophysics, 1973
- The binding of hydrogen and calcium ions by Tamm-Horsfall glycoproteinBiochimica et Biophysica Acta (BBA) - Protein Structure, 1972
- Laser light scattering studies on urinary glycoproteinBiochimica et Biophysica Acta (BBA) - Protein Structure, 1971
- Tamm–Horsfall urinary glycoprotein. The subunit structureBiochemical Journal, 1970
- Subunits of Tamm–Horsfall glycoproteinBiochemical Journal, 1970
- Immunofluorescent localization of TAMM-HORSFALL mucoproteinCellular and Molecular Life Sciences, 1966
- Studies on glycoproteins X. Equilibrium measurements on influenza virus-glycoproteins systemsBiochimica et Biophysica Acta, 1963