Steroidal Ureas as Enantioselective Receptors for an N-Acetyl α-Amino Carboxylate
- 1 December 2002
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 4 (26) , 4639-4642
- https://doi.org/10.1021/ol027009l
Abstract
Cholic acid has been elaborated into three regioisomeric bis-carbamoylureas, which have been investigated as enantioselective receptors for N-acetyl phenylalanine. l/d selectivities, peaking at 5:1, have been determined by a sensitive and rapid MS-based extraction method that should be generalizable to related systems.Keywords
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