Biosynthesis of rutacridone in tissue cultures of Ruta graveolens L.
- 1 June 1982
- journal article
- research article
- Published by Springer Nature in Plant Cell Reports
- Vol. 1 (4) , 168-171
- https://doi.org/10.1007/bf00269190
Abstract
The dihydrofuroacridone, rutacridone, is the main alkaloid in tissue cultures of Ruta graveolens L. strain R-19. The biosynthesis of this particular acridone alkaloid was investigated by using calluses and suspension cultures of strain R-19. Anthranilic acid is specifically incorporated into ring A of rutacridone. Some further evidence was provided that acetate via a polyketide is involved in acridone biosynthesis. Mevalonic acid gave a poor incorporation into rutacridone. Thus the origin of the isopropyldihydrofuran moiety of the investigated alkaloid is still obscure.Keywords
This publication has 16 references indexed in Scilit:
- Synthesis of (±)-RutacridoneHETEROCYCLES, 1981
- The Effect of Medium Modification and Selected Precursors on Sterol Production by Short-Term Callus Cultures of Euphorbia tirucalliJournal of Natural Products, 1979
- 13C-NMR-spektren einiger acridon-alkaloidePhytochemistry, 1979
- Biomimetic synthesis of acridone alkaloidsJournal of the Chemical Society, Perkin Transactions 1, 1977
- Intramolecular cyclisation of 2-aminobenzophenones; a new 9-acridone synthesisJournal of the Chemical Society, Perkin Transactions 1, 1976
- The biogenesis of acridone alkaloidsJournal of the Chemical Society D: Chemical Communications, 1970
- Studies using radioisotopes. III. The biosynthesis of acridone alkaloidsAustralian Journal of Chemistry, 1969
- Studies using radioisotopes. I. The incorporation of anthranilic acid into acronidineAustralian Journal of Chemistry, 1968
- Synthase radioaktiv markierter Verbindungen X. Mitteilung [1]; Synthese von 14C‐carboxylmarkierter 3‐Hydroxyanthranilsäure und AnthranilsäureZeitschrift für Chemie, 1963
- A Revised Medium for Rapid Growth and Bio Assays with Tobacco Tissue CulturesPhysiologia Plantarum, 1962