Loss of expression of the uvomorulin gene in compaction-defective embryonal carcinoma cells
- 1 November 1991
- journal article
- Published by Springer Nature in Somatic Cell and Molecular Genetics
- Vol. 17 (6) , 617-619
- https://doi.org/10.1007/bf01233627
Abstract
The lack of uvomorulin protein in the 6B(NG)C25 subline of H6 embryonal carcinoma cells is due to loss of expression of the uvomorulin gene, without evidence of gross alteration in the gene itself. This suggests that the dominant mutation in 6B(NG)C25 may involve atrans-acting factor involved in the regulation of uvomorulin gene expression.Keywords
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