Total Synthesis of (−)-Ratjadone
- 3 April 2001
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 3 (9) , 1383-1386
- https://doi.org/10.1021/ol015753k
Abstract
[reaction in text] A convergent asymmetric synthesis of (-)-ratjadone (1) has been achieved, confirming the assignments of stereochemistry for the naturally occurring antifungal metabolite.Keywords
This publication has 48 references indexed in Scilit:
- Zirconocene−Zinc Transmetalation and in Situ Catalytic Asymmetric Addition to AldehydesThe Journal of Organic Chemistry, 1998
- Asymmetric Total Synthesis of Callystatin A: Asymmetric Aldol Additions with Titanium Enolates of AcyloxazolidinethionesJournal of the American Chemical Society, 1998
- A new synthesis of 1-phenylthio- and 1-alkylamino-4-nitrobuta-1,3-dienesJournal of the Chemical Society, Perkin Transactions 1, 1996
- Antibiotics from Gliding Bacteria, LXIII. Ratjadone: A New Antifungal Metabolite from Sorangium cellulosumEuropean Journal of Organic Chemistry, 1995
- High-field FT NMR application of Mosher's method. The absolute configurations of marine terpenoidsJournal of the American Chemical Society, 1991
- Activation of 6-endo over 5-exo hydroxy epoxide openings. Stereoselective and ring selective synthesis of tetrahydrofuran and tetrahydropyran systemsJournal of the American Chemical Society, 1989
- Chiral synthesis via organoboranes. 21. Allyl- and crotylboration of .alpha.-chiral aldehydes with diisopinocampheylboron as the chiral auxiliaryThe Journal of Organic Chemistry, 1989
- Catalytic asymmetric epoxidation and kinetic resolution: modified procedures including in situ derivatizationJournal of the American Chemical Society, 1987
- ASYMMETRIC REDUCTION OF SIMPLE ACHIRAL KETONES WITH LITHIUM ALUMINUM HYDRIDE PARTIALLY DECOMPOSED BY (−)-N-METHYLEPHEDRINE AND N-ETHYLANILINEChemistry Letters, 1980
- Asymmetric reduction of αβ-unsaturated ketones with lithium aluminium hydride partially decomposed by (–)-N-methylephedrine and N-ethylanilineJournal of the Chemical Society, Chemical Communications, 1980