Effect of Stainless Steel Corrosion Products on in Vitro Biomineralization
- 1 October 1999
- journal article
- research article
- Published by SAGE Publications in Journal of Biomaterials Applications
- Vol. 14 (2) , 113-168
- https://doi.org/10.1177/088532829901400202
Abstract
Osteoblast-like cell cultures have been used as in vitro models to study the interactions of bone tissue with biomaterials and their degradation products. This work reviews the effects of AISI 316L stainless steel (SS) corrosion products on the osteoblastic behavior of rat and human bone cell cultures. Results suggest that such products affect, in a dose-]dependent manner, the proliferation and differentiation of osteoblastic cells; these effects depend on the developmental stage of the osteoblastic cells. Above certain nonlethal concentrations, SS corrosion products prevent the mineralization of the extracellular matrix, a process that reflects the complete expression of the osteoblastic phenotype.Keywords
This publication has 83 references indexed in Scilit:
- Iron determination in osteoblast‐like cell culture medium by adsorptive cathodic stripping voltammetry with a mercury microelectrodeElectroanalysis, 1997
- Effect of metal ions on the formation and function of osteoclastic cellsin vitroJournal of Biomedical Materials Research, 1997
- Nickel determination in osteoblast‐like cell culture medium by adsorptive cathodic stripping voltammetry with a mercury microelectrodeElectroanalysis, 1997
- Potentiometric determination of total and ionized calcium in osteoblast‐like cell culture mediumElectroanalysis, 1996
- Human bone tissue formation in diffusion chamber culture in vivo by bone-derived cells and marrow stromal fibroblastic cellsBone, 1995
- Acute toxicity of metal ions in cultures of osteogenic cells derived from bone marrow stromal cellsJournal of Applied Biomaterials, 1995
- Mini‐review: Osteoblasts: An in vitro model of bone‐implant interactionsBiotechnology & Bioengineering, 1994
- The biologic responses to orthopedic implants and their wear debrisClinical Materials, 1992
- Release of metal ions from dental implant materials in vivo: Determination of Al, Co, Cr, Mo, Ni, V, and Ti in organ tissueJournal of Biomedical Materials Research, 1991
- Isolation of serum protein organometallic corrosion products from 316LSS and HS‐21 in vitro and in vivoJournal of Biomedical Materials Research, 1984