SODIUM RETENTION IN THE OPOSSUM1

Abstract
The effects of adrenal extract, Na factor fraction and desoxy-corticosterone were studied in the normal opossum. Adrenal extract produced moderate Na retention in some animals but this was considerably less than would be produced by the same amt. of extract in dogs. The precipitated Na factor likewise possessed little potency. Desoxycorticosterone acetate was more effective, causing retention of Na at first, to be followed later by excretion. The opossum appears to be less responsive to these Na-retaining sub-stances than are other mammals.

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