Simvastatin reduces caspase-3 activation and inflammatory markers induced by hypoxia–ischemia in the newborn rat
- 31 January 2006
- journal article
- Published by Elsevier in Neurobiology of Disease
- Vol. 21 (1) , 119-126
- https://doi.org/10.1016/j.nbd.2005.06.014
Abstract
No abstract availableKeywords
Funding Information
- Università degli Studi di Urbino Carlo Bo
This publication has 48 references indexed in Scilit:
- New therapeutic strategies in perinatal stroke.Current Drug Targets-CNS & Neurological Disorders, 2004
- Peripheral Treatment with Enoxaparin, a Low Molecular Weight Heparin, Reduces Plaques and β-Amyloid Accumulation in a Mouse Model of Alzheimer's DiseaseJournal of Neuroscience, 2004
- Prophylactic but Not Delayed Administration of Simvastatin Protects Against Long-Lasting Cognitive and Morphological Consequences of Neonatal Hypoxic-Ischemic Brain Injury, Reduces Interleukin-1β and Tumor Necrosis Factor-α mRNA Induction, and Does Not Affect Endothelial Nitric Oxide Synthase ExpressionStroke, 2003
- 3-Hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors, atorvastatin and simvastatin, induce apoptosis of vascular smooth muscle cells by downregulation of Bcl-2 expression and Rho A prenylationAtherosclerosis, 2002
- Simvastatin Protects Against Long-Lasting Behavioral and Morphological Consequences of Neonatal Hypoxic/Ischemic Brain InjuryStroke, 2001
- Mevastatin, an HMG-CoA Reductase Inhibitor, Reduces Stroke Damage and Upregulates Endothelial Nitric Oxide Synthase in MiceStroke, 2001
- Synergistic Activation of Caspase-3 by m-Calpain after Neonatal Hypoxia-IschemiaJournal of Biological Chemistry, 2001
- Reduction of Stroke Events With PravastatinCirculation, 2001
- Long-lasting behavioral alterations following a hypoxic/ischemic brain injury in neonatal ratsBrain Research, 2000
- Caspases: the executioners of apoptosisBiochemical Journal, 1997