From Bedside to Bench: Research Agenda for Frailty
- 3 August 2005
- journal article
- perspectives
- Published by American Association for the Advancement of Science (AAAS) in Science of Aging Knowledge Environment
- Vol. 2005 (31) , pe24-24
- https://doi.org/10.1126/sageke.2005.31.pe24
Abstract
The American Geriatrics Society sponsored a working conference in January 2004, funded by the National Institute on Aging, to establish the state of the art in frailty research and to set a research agenda for the future. The invited participants included senior basic biologists, epidemiologists, geneticists, and clinical investigators who study aging-related issues. This article summarizes the central theoretical observations on frailty and research needs and opportunities presented and discussed at this conference, and lays out an agenda for future research on frailty.Keywords
This publication has 33 references indexed in Scilit:
- Frailty and Its Definition: A Worthy ChallengeJournal of the American Geriatrics Society, 2005
- Clinical Global Impression of Change in Physical Frailty: Development of a Measure Based on Clinical JudgmentJournal of the American Geriatrics Society, 2004
- GenAge: a genomic and proteomic network map of human ageingFEBS Letters, 2004
- Frailty--The Search For Underlying CausesScience of Aging Knowledge Environment, 2004
- Nuclear Translocation of Nuclear Transcription Factor-κB by α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptors Leads to Transcription of p53 and Cell Death in Dopaminergic NeuronsMolecular Pharmacology, 2003
- Systems Biology: A Brief OverviewScience, 2002
- Reverse Engineering of Biological ComplexityScience, 2002
- Telomeres, aging and cancer: In search of a happy endingOncogene, 2002
- How to Select a Frail Elderly Population? A Comparison of Three Working DefinitionsJournal of Clinical Epidemiology, 1999
- Failure to Thrive: Paradigm for the Frail ElderThe Gerontologist, 1989